Pregnancy and Lupus: Planning for a Healthy Journey Together

Receiving a lupus diagnosis doesn’t mean motherhood is out of reach. While systemic lupus erythematosus (SLE) requires thoughtful planning and monitoring during pregnancy, thousands of women with lupus successfully carry healthy babies to term each year. At Arthritis and Rheumatology of Georgia (ARG), our experienced rheumatologists work closely with expectant mothers to protect both maternal and fetal health throughout every stage of this important journey. With offices in Sandy Springs and Woodstock, we’ve supported Atlanta families with expert autoimmune care for over 40 years.

Understanding Lupus and Pregnancy

Systemic lupus erythematosus (SLE) is a chronic autoimmune condition that causes the immune system to attack healthy tissues, potentially affecting the joints, skin, kidneys, heart, lungs, and other organs. For women with lupus, pregnancy introduces additional hormonal changes that can influence disease activity and increase the risk of flares.

With thoughtful planning and expert care, many women with lupus go on to have healthy pregnancies and babies. Success begins before conception. According to Dr. Paula Tanasa, a Top Doctor recognized by Atlanta Magazine, “A successful pregnancy with lupus is absolutely possible when we work together as a team. The ideal scenario involves achieving lupus remission before conception and ensuring patients are on pregnancy-safe medications.”

At Arthritis and Rheumatology of Georgia (ARG), we believe in empowering women with lupus to navigate pregnancy confidently, supported by a coordinated care team every step of the way.

Pre-Conception Planning: Laying the Groundwork for Success

To optimize outcomes, women with lupus should aim to be in remission prior to pregnancy. During this time, several critical steps are taken:

  • Medication Review – Some lupus medications, like methotrexate and mycophenolate, can be harmful during pregnancy and must be stopped or switched to safer options.
  • Stable Disease Management – Active lupus during pregnancy increases the risk of complications and can lead to poor outcomes for both mother and baby.
  • Health Optimization – Managing blood pressure, monitoring kidney health, and supplementing with folic acid are all part of preparing the body for pregnancy.

Safe Medications for Lupus in Pregnancy

Several lupus medications are considered safe during pregnancy. Hydroxychloroquine (Plaquenil) is often continued because it can reduce flares and prevent complications. Low-dose corticosteroids like prednisone are also commonly used if needed.

Some immunosuppressive drugs, such as azathioprine, may be continued during pregnancy under expert supervision. Our team works to tailor each treatment plan to the patient’s medical history, current disease activity, and pregnancy goals.

Monitoring During Pregnancy

Pregnancy for lupus patients involves additional monitoring to help detect complications early. At ARG, we coordinate closely with each patient’s obstetric team, often including maternal-fetal medicine specialists.

  • Routine lab testing to monitor disease activity and kidney function
  • Blood pressure monitoring to watch for signs of preeclampsia
  • Fetal monitoring, especially in patients with certain autoantibodies that can affect the baby’s heart or development

With in-house lab capabilities at our Sandy Springs and Woodstock offices, we’re able to provide rapid test results and adjust care plans promptly.

Managing Flares Safely

Despite all efforts, flares can still happen. It’s important to distinguish normal pregnancy changes from actual lupus symptoms—fatigue, joint pain, and swelling are common to both. Our clinical team is skilled in evaluating and addressing these differences.

When treatment is needed, we prioritize therapies that are safe for both mother and baby. This may include medication adjustments or temporary increases in dosage under careful monitoring.

Delivery and Postpartum Care

Most women with well-controlled lupus can expect a vaginal delivery, although cesarean birth may be necessary in certain situations. The postpartum period is a high-risk time for lupus flares due to hormonal shifts, making continued medical monitoring essential.

Breastfeeding is often possible for women with lupus. Many medications are safe during nursing, while others may require adjustments. Our team works closely with each patient to provide personalized guidance and ensure the safest choices for both mother and baby.

Support and Collaboration for a Healthy Pregnancy

Managing pregnancy with lupus requires collaboration—between the patient, rheumatologist, OB-GYN, and often other specialists like nephrologists. At ARG, our providers prioritize communication with referring physicians across Atlanta to ensure consistent, integrated care.

Frequently Asked Questions About Pregnancy and Lupus

  • Can I get pregnant if I have lupus? Yes. Most women with lupus can conceive and carry a baby to term. Disease control and medication safety are key.
  • Will pregnancy make my lupus worse? Some women experience flares during pregnancy. Proper planning, close monitoring, and coordinated care help manage changes and support a healthy outcome.
  • What are the risks of pregnancy with lupus? Women with lupus may face increased risks such as preeclampsia, preterm birth, pregnancy loss, and intrauterine growth restriction. With expert care and close monitoring, these risks can often be managed to support a healthy pregnancy.
  • Can I take lupus medications while pregnant or breastfeeding? Many lupus medications, including hydroxychloroquine and low-dose steroids, are safe. We tailor plans to each patient’s needs.
  • Should I avoid pregnancy if I’ve had kidney issues from lupus? Not necessarily. If your kidney function is stable and lupus is well-controlled, pregnancy may still be safe with close supervision.
  • How soon can I return to my normal medications after pregnancy? That depends on whether you’re breastfeeding and your overall condition. We help develop a clear plan in advance.

Moving Forward with Confidence

With the right planning and support, pregnancy with lupus is entirely possible. At Arthritis and Rheumatology of Georgia, we’re proud to partner with patients on their journey to motherhood—combining expert care with long-term disease management.

With offices in Sandy Springs and Woodstock, our team is here to support you every step of the way. Ready to take the next step? Visit www.argmd.net or call 404-255-5956 to schedule your consultation.

Arthritis and Rheumatology of Georgia
Sandy Springs & Woodstock
www.argmd.net | 404-255-5956

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